• Product Name
  Dscam Mouse Monoclonal Antibody (DS2-176)
• Host
  Mouse
• Clonality
  Monoclonal
• Clone ID
  DS2-176
• DataSHEET
  View Datasheet (PDF)
• Isotype
  IgG1
• Conjugation
  None
• Reactivity
  Chicken, mouse
• Specificity
  Full length
• Storage Buffer
  Lyophilized antibody can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage.
• Format
  100 µg
• Background
  Down syndrome cell adhesion molecule (Dscam) is a cell adhesion molecule that plays a role in neuronal self-avoidance. It promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Dscam mediates, within retinal amacrine and ganglion cell subtypes, both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. It is the receptor for netrin that is required for axon guidance independently of and in collaboration with the receptor DCC. In spinal cord development, it plays a role in guiding commissural axons during projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Dscam enhances netrininduced phosphorylation of PAK1 and FYN. It mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38. Dscam interacts with DCC, Netrin-1, PAK1 and RAC1.

Medimabs麦吉尔大学的一组研究人员于2006年在魁北克蒙特利尔成立，以确保本地研究人员能够以负担得起的价格获得最新的高质量研究抗体。我们的目标是提供定制抗体生成服务，并提供比大多数研究实验室自己能做的更好，更快和更便宜的服务。 
 
截至2018年，我们的设施现在位于蒙特利尔的中心，周围是蒙特利尔的生命科学集群，周围有许多生物技术公司，大学，研发机构，主要的主要医疗保健网络和医院。新的场所，但公司的重点仍然保持不变，因为它具有提供新的创新服务和可满足您所有抗体需求的完整“一站式服务”的额外好处。