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主营:单克隆抗体,多克隆抗体
℡ 4000-520-616
℡ 4000-520-616
Medimabs/HMG Co A reductase Rabbit Polyclonal Antibody/100 µL/MM-0197
产品编号:MM-0197
市  场 价:¥5100.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>单克隆抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$255.00
品      牌: Medimabs
公      司:Medimabs inc.
公司分类:
Medimabs/HMG Co A reductase Rabbit Polyclonal Antibody/100 µL/MM-0197
商品介绍
Target:
HMG Co A reductase
Target background:
HMG-CoA reductase (also known as 3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGCR) is a transmembrane glycoprotein involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis; it is a ubiquitously expressed glycoprotein that is bound to the membrane of the endoplasmic reticulum. HMG-CoA reductase is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. HMG-CoA is inhibited by statin, a class of cholesterol-lowering drugs which lower plasma cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor.
Target alias:
3-hydroxy-3-methyl-glutaryl-CoA reductase, HMGCR
Immunogen:
Full length protein
Specificity: The antibody recognizes the HMG CoA reductase
Clone ID:
---
Preservative:
None
Format:
Lyophilized serum
Recommend starting dilution:
If reconstituted with deionized water in 100 µl: WB 1:500, IF 1:50-1:100. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍

Medimabs麦吉尔大学的一组研究人员于2006年在魁北克蒙特利尔成立,以确保本地研究人员能够以负担得起的价格获得最新的高质量研究抗体。我们的目标是提供定制抗体生成服务,并提供比大多数研究实验室自己能做的更好,更快和更便宜的服务。 
 
截至2018年,我们的设施现在位于蒙特利尔的中心,周围是蒙特利尔的生命科学集群,周围有许多生物技术公司,大学,研发机构,主要的主要医疗保健网络和医院。新的场所,但公司的重点仍然保持不变,因为它具有提供新的创新服务和可满足您所有抗体需求的完整“一站式服务”的额外好处。 

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