• Product Name
  Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified
• Host
  Mouse
• Clonality
  Monoclonal
• Clone ID
  6A4
• DataSHEET
  View Datasheet (PDF)
• Isotype
  IgG1
• Conjugation
  None
• Reactivity
  Mouse
• Specificity
  Full length
• Format
  100 µg
• Background
  The SGT/UBP protein (also known as small glutamine-rich tetratricopeptide repeat (TPR)- containing protein A, Alpha-SGT, Vpu-Binding Protein, UBP, SGTA, SGT or SGT1) is a ubiquitously expressed cochaperone protein which contains three TPR protein-protein interaction repeats. SGT/UBP binds to Hsp70, negatively affecting its function. SGT/UBP interacts with the Viral protein U (Vpu) and Group specific Antigen (Gag) proteins from HIV-1 and with the nonstructural protein NS-1 of parvovirus H-1; the protein/chaperone complex is thought to be involved in Vpu function and HIV particle exit and in parvovirus DNA replication. SGT/UBP also interacts with SARS-CoV Accessory Protein 7a, although the function remains unknown. Furthermore, SGT/UBP is believed to be a component of the androgen receptor (AR)-chaperone-co-chaperone complex, acting as a co-chaperone involved in androgen signaling.

Medimabs麦吉尔大学的一组研究人员于2006年在魁北克蒙特利尔成立，以确保本地研究人员能够以负担得起的价格获得最新的高质量研究抗体。我们的目标是提供定制抗体生成服务，并提供比大多数研究实验室自己能做的更好，更快和更便宜的服务。 
 
截至2018年，我们的设施现在位于蒙特利尔的中心，周围是蒙特利尔的生命科学集群，周围有许多生物技术公司，大学，研发机构，主要的主要医疗保健网络和医院。新的场所，但公司的重点仍然保持不变，因为它具有提供新的创新服务和可满足您所有抗体需求的完整“一站式服务”的额外好处。